Nephrocor™ provides fast, concise, and definitive reporting on each case. Your report will include photomicrographs including electron microscopy performed in-house on every case. Our nephropathologists follow a structured reporting method allowing your practice to receive reports that are easy to read and images that support the diagnosis for patient education.
Sections show one core consisting of renal cortex and medulla.
Glomeruli: Approximately 35 glomeruli are examined. None of the glomerular is obsolescent or scarred. The mesangial areas are diffusely hypercellular and there is segmental endocapillary hypercellularity in approximately 30% of the glomeruli. Some areas of endocapillary hypercellularity have intact and pycnotic neutrophils. PAS shows diffusely increased mesangial matrix and Jones silver shows occasional double contour capillaries consistent with mesangial interposition. Tubules and interstitium: The tubules and interstitium appear essentially normal except for very mild, focal, interstitial fibrosis and inflammation. Vessels: Interlobular arteries (two seen) and arterioles are normal. Controls: Masson trichrome, PAS and Jones silver stains were necessary for evaluation of this biopsy and showed normal staining patterns with internal control tissue matrix structures.
PAS: segmental endocapillary
glomerulonephritis
Number of glomeruli examined: 12-14
IgA: diffuse, mesangial granular, 2+
IgG: diffuse, mesangial granular, 2+, segmental capillary 1+, speckled nuclear
IgM: diffuse, mesangial granular, 1+
C3: focal, mesangial granular, 3+
C1q: diffuse, mesangial, 3+
Kappa: diffuse, mesangial granular, 2+, segmental capillary 1+, speckled nuclear
Lambda: diffuse, mesangial granular, 3+, segmental capillary 1+, speckled nuclear
Fibrinogen: negative
IgG: mesangial deposits,
speckled ANA
subendothelial deposits
DIAGNOSIS: Kidney, right, needle biopsy: Focal lupus nephritis, ISN/RPS Class III(A).
